A city skyline reflected in a calm body of water, a bridge, and a sunset sky.

Uptown Central Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Uptown Central Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 25 - Jan 29

    La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW + Flight

    Medical Center District
    4 nights
    3.0 star property
    8.4/10 - Very good (3,773 reviews)
    Roundtrip • Vancouver (YVR) - San Antonio (SAT)
    YVR - SAT • 1 stop SAT - YVR • 1 stop
    CA $952
    CA $781
    per traveller
    found 6 hours ago
    La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
  • Dec 25 - Dec 30

    Tx Home Group- San Antonio + Flight

    Midtown
    5 nights
    2.0 star property
    7.8/10 - Good (10 reviews)
    Roundtrip • Toronto (YYZ) - San Antonio (SAT)
    YYZ - SAT • 1 stop SAT - YYZ • 1 stop
    Save 100% on your flight
    CA $1,659
    CA $999
    per traveller
    found 1 day ago
    Tx Home Group- San Antonio
  • Dec 19 - Dec 23

    Sítio El Tropicano + Flight

    Downtown San Antonio
    4 nights
    4.5 star property
    Roundtrip • Toronto (YTO) - San Antonio (SAT)
    YTZ - SAT • 1 stop SAT - YYZ • 1 stop
    CA $1,557
    CA $1,155
    per traveller
    found 13 hours ago
    Sítio El Tropicano
  • Jan 15 - Jan 20

    Hyatt Regency Hill Country Resort and Villas + Flight

    Far West Side
    5 nights
    4.0 star property
    8.8/10 - Excellent (1,000 reviews)
    "It’s alright - expensive for what your money buys"
    Reviewed November 4, 2026
    Roundtrip • St. John's (YYT) - San Antonio (SAT)
    YYT - SAT • 2 stops SAT - YYT • 2 stops
    CA $2,938
    CA $2,248
    per traveller
    found 2 hours ago
    Hyatt Regency Hill Country Resort and Villas
  • Jan 7 - Jan 12

    Hotel Contessa + Flight

    Downtown San Antonio
    5 nights
    4.0 star property
    9.0/10 - Wonderful (4,050 reviews)
    "Great hotel location! Staff was amazing and professional."
    Reviewed November 7, 2026
    Roundtrip • Toronto (YYZ) - San Antonio (SAT)
    YYZ - SAT • 1 stop SAT - YYZ • 1 stop
    CA $1,438
    CA $1,115
    per traveller
    found 1 day ago
    Hotel Contessa

Where to stay in Uptown Central

Find the best Uptown Central areas and neighborhoods for the activities you enjoy most.

Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Medical Center District

While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.

Discover the most popular places to visit in Uptown Central

What to do near Uptown Central

Uptown Central Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How much does an Uptown vacation package cost?

The most affordable Uptown package is CA $781, so your dream trip can become a reality — without spending an arm and a leg. Bundle flights, hotels and car rentals to create a package that suits your travel style.

How do I get a cheap travel package to Uptown?

Combine your hotel and flight bookings, throw in extras such as activities, and save with an Uptown vacation package. You won't just land exciting discounts on your getaway — you'll have lots of choice within your reach too. When you book through Expedia, you can select from more than 550 partner airlines and 1,000,000 properties worldwide. Your next epic adventure starts right here, right now!

Where should I stay in Uptown?

A journey to Uptown isn't complete without stopping by San Antonio Zoo and Aquarium and San Antonio Botanical Gardens. Look for somewhere to stay right nearby for quick access to these fantastic attractions.

What are the top hotels in Uptown?

Get your vacation off to a good start by reserving a room at Marriott San Antonio Airport. It's one of most sought-after hotels in Uptown. Another welcoming option is Little Gem In Olmos Park.

How far in advance should I book my Uptown vacation?

Get rewarded with the biggest variety at the cheapest prices by booking your adventure to Uptown early. Air carriers usually advertise flight tickets anywhere up to a year prior to departure, so start your planning as soon as you can. Having said that, Expedia is constantly working to give you the best deals around, so it's never a bad time to book your dream vacation!

What does an Expedia Uptown travel package include?

Travel packages include flights, rental cars and hotels, but you can mix and match them to create your perfect Uptown vacation. You can also add on fun things like activities and experiences once you've made your booking. You're in control! When you bundle your bookings with Expedia, you'll get discounts you won't find elsewhere.

What should I know before booking an Uptown travel package?

So many places to explore, so many things to do. With a package, you'll be able to cross more of them off your list. Combine your hotels, flights and rental cars and enjoy big savings.

Can I choose my airline with an Uptown Expedia vacation package?

Yes, and with over 550 airlines to pick from all over the world, you've got lots of choice. Browse the available options and see which airline best suits your needs and budget.

If I'm not able to travel, can I cancel my Uptown vacation package?

It's difficult to predict what tomorrow might bring, so it's comforting to know that you can change or cancel your Uptown vacation package. If you made your booking in the last 24 hours, you may be entitled to a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Check our Customer Service Portal for further details.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.